Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 9/20 | 0.59 |
| ▸ | GRIK3 | Q13003 | 8/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.59 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.59 |
| ▸ | GRIK5 | Q16478 | 6/20 | 0.59 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687295 | 0.91 | GRIK3 (0.54) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8687487 | 0.87 | GRIK3 (0.50) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8689701 | 0.85 | GRIA2 (0.63) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8687224 | 0.85 | GRIA2 (0.52) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8687227 | 0.84 | GRIA2 (0.60) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8688995 | 0.83 | GRIK3 (0.56) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8686996 | 0.83 | GRIA2 (0.51) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8689652 | 0.83 | GRIA2 (0.51) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8591048 | 0.82 | GRIA2 (0.47) | GRIA2GRIK3GRIK2GRIK1GRIA1 | |
| SCHEMBL8541588 | 0.82 | GRIK3 (0.67) | GRIA2GRIK3GRIK2GRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1995035289-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |