Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 9/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.51 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689652 | 0.88 | GRIA2 (0.51) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8692289 | 0.83 | GRIA2 (0.59) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8687295 | 0.83 | GRIK3 (0.54) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8689701 | 0.82 | GRIA2 (0.63) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8593265 | 0.81 | CA12 (0.48) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8687782 | 0.81 | GRIA1 (0.62) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8687224 | 0.81 | GRIA2 (0.52) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8687487 | 0.81 | GRIK3 (0.50) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8687841 | 0.81 | GRIA2 (0.64) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8591048 | 0.77 | GRIA2 (0.47) | GRIA2GRIA1GRIA3GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1995035289-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |