Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693993 | 0.89 | LDHA (0.56) | IDO1LDHASLC6A4CYP1A2CYP2D6 | |
| SCHEMBL8692821 | 0.83 | NQO1 (0.45) | ACACB | |
| SCHEMBL9068904 | 0.83 | LTA4H (0.56) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8694880 | 0.80 | FFAR1 (0.46) | ACACB | |
| SCHEMBL3742486 | 0.77 | SLC6A4 (0.58) | IDO1LDHASLC6A4CYP1A2CYP2D6 | |
| SCHEMBL28108544 | 0.76 | FOLH1 (0.50) | IDO1CYP1A2 | |
| SCHEMBL7277160 | 0.75 | LDHA (0.43) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8692217 | 0.75 | LDHA (0.50) | IDO1LDHASLC6A4CYP1A2CYP2D6 | |
| SCHEMBL2265781 | 0.75 | SLC6A4 (0.61) | IDO1LDHASLC6A4CYP1A2CYP2D6 | |
| SCHEMBL7294911 | 0.75 | SLC6A4 (0.61) | IDO1LDHASLC6A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | claimed |
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5670531-A | ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-09-23 | — | — | US | disclosed |