Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | KDM6A | O15550 | 1/20 | 0.62 |
| ▸ | KDM4A | O75164 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KDM5C | P41229 | 1/20 | 0.62 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.62 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.62 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10404502 | 0.98 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Deferiprone SCHEMBL6400926 | 0.93 | KDM4E (0.76) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL6995058 | 0.84 | KDM4E (0.62) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6997040 | 0.82 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL18117860 | 0.82 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL8615538 | 0.82 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL4546216 | 0.81 | KDM4E (0.58) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Deferiprone SCHEMBL7224598 | 0.80 | KDM4E (0.67) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL5515462 | 0.79 | KDM4E (0.47) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL9700190 | 0.79 | KDM4E (0.56) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567156-B1 | HYDROXYPYRIDINONES FOR THE LOCAL TREATMENT OF SKIN MICROCIRCULATORY DISORDERS | RELIVIA SRL (IT) | 2009-08-26 | — | — | EP | claimed |
| US-7160482-B2 | Composition comprising an oxidizing and complexing compound | IMEC VZW (BE) | 2007-01-09 | — | — | US | claimed |
| US-20050009207-A1 | Composition comprising an oxidizing and complexing compound | VERSUM MATERIALS US, LLC | 2005-01-13 | — | — | US | claimed |
| US-11654137-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| EP-2684222-B1 | ALUMINIUM OXIDE PASTES AND METHOD FOR THE USE THEREOF | MERCK PATENT GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
| CN-103493220-B | Alumina paste and method of use thereof | 默克专利股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| US-9580610-B2 | Aluminium oxide pastes and process for the use thereof | MERCK PATENT GMBH (DE) | 2017-02-28 | — | — | US | disclosed |
| CN-103429681-B | Printable alumina ink formulations | 默克专利股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| EP-0829104-A1 | HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1998-03-18 | — | — | EP | disclosed |
| EP-0808103-A1 | PROTEIN HYDROXYLATION INHIBITORS FOR FIBROPROLIFERATIVE DISORDERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-11-26 | — | — | EP | disclosed |
| EP-0729648-A4 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LTD (AU) | 1997-01-02 | — | — | EP | disclosed |
| WO-1996035239-A1 | HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-11-07 | — | — | WO | disclosed |
| EP-0729648-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1996-09-04 | — | — | EP | disclosed |
| WO-1996022021-A1 | PROTEIN HYDROXYLATION INHIBITORS FOR FIBROPROLIFERATIVE DISORDERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995012219-A1 | STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS | UNISEARCH LIMITED (AU) | 1995-05-04 | — | — | WO | disclosed |
| WO-1989009211-A1 | PROCESS FOR PRODUCING PYRID-4-ONES | THE ROYAL FREE HOSPITAL SCHOOL OF MEDICINE (GB) | 1989-10-05 | — | — | WO | disclosed |
| EP-0335745-A1 | Process for producing pyrid-4-ones | THE ROYAL FREE HOSPITAL SCHOOL OF MEDICINE (GB) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11654137-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | KDM1B, KDM3A, KDM1A | KDM4E 10/4885KDM6A 18/4885KDM4A 5/4885 |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | KDM4E 2785/4885KDM6A 3395/4885KDM4A 3662/4885 |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | FH, FECH, FPGS | KDM4E 2376/4885KDM6A 3191/4885KDM4A 3448/4885 |
| US-20050009207-A1 | Composition comprising an oxidizing and complexing compound | C5, SCO2, NOX4 | KDM4E 2769/4885KDM6A 2283/4885KDM4A 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.