Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688119 | 0.92 | MRGPRX4 (0.43) | CNR1MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL8689074 | 0.85 | LMNA (0.39) | RHEBLMNAMAPK14CNR1FAAH | |
| SCHEMBL7354793 | 0.80 | HDAC8 (0.45) | RHEBLMNAMAPK14MRGPRX4FAAH | |
| SCHEMBL8440689 | 0.77 | HDAC8 (0.49) | RHEBFAAHMGLLHDAC8HDAC6 | |
| SCHEMBL8690877 | 0.76 | ADORA2A (0.47) | HDAC8HDAC6ADORA2ADPP4AR | |
| SCHEMBL7359931 | 0.71 | MRGPRX4 (0.48) | MRGPRX4HDAC8HDAC6PDE4APDE4B | |
| SCHEMBL8439171 | 0.70 | MRGPRX4 (0.49) | MRGPRX4HDAC8HDAC6DPP4AR | |
| SCHEMBL8443456 | 0.68 | HDAC8 (0.52) | MRGPRX4HDAC8HDAC6DPP4AR | |
| SCHEMBL8438863 | 0.65 | F10 (0.48) | — | |
| SCHEMBL8439957 | 0.62 | CFTR (0.58) | CNR1FAAHHDAC8HDAC6ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728697-A | INHIBITORS OF FACTOR X | BERLEX LABORATORIES, INC. (US) | 1998-03-17 | — | — | US | disclosed |