Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17028384 | 0.86 | LMNA (0.53) | MAOBBCHEMAOANR4A2ALOX5 | |
| SCHEMBL10339033 | 0.82 | SLC6A2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL1268719 | 0.80 | MAOB (0.81) | MAOBBCHECYP4F2CYP4A11MAOA | |
| SCHEMBL11229037 | 0.79 | MRGPRX4 (0.47) | — | |
| SCHEMBL28182081 | 0.78 | MAOB (0.79) | MAOBBCHECYP4F2CYP4A11MAOA | |
| SCHEMBL11526012 | 0.78 | KDM4E (0.41) | — | |
| SCHEMBL13720929 | 0.76 | MAOB (0.60) | MAOBBCHECYP4F2CYP4A11MAOA | |
| SCHEMBL8693129 | 0.76 | MAPT (0.51) | APP | |
| SCHEMBL7752555 | 0.76 | CA4 (0.40) | — | |
| SCHEMBL2282297 | 0.76 | CA4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0151513-A1 | Inotropic agent | ELI LILLY AND COMPANY (US) | 1985-08-14 | — | — | EP | disclosed |