Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638364 | 0.83 | AKR1B1 (0.45) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5871962 | 0.83 | AKR1B1 (0.45) | AKR1B1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14601731 | 0.83 | ALDH1A1 (0.48) | AKR1B1MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5598431 | 0.80 | AKR1B1 (0.43) | AKR1B1PSIP1MAPTSMN1; SMN2POLB | |
| SCHEMBL24625403 | 0.77 | PSIP1 (0.54) | PSIP1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8698751 | 0.76 | AKR1B1 (0.47) | AKR1B1MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14601735 | 0.75 | KDM4E (0.55) | AKR1B1MAPTALDH1A1GAANPSR1 | |
| SCHEMBL14458213 | 0.75 | ALDH1A1 (0.44) | AKR1B1MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14601732 | 0.74 | KMT2A (0.47) | AKR1B1MAPTALDH1A1POLBKMT2A | |
| SCHEMBL2906762 | 0.74 | AKR1B1 (0.50) | AKR1B1MAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807891-A | RETROVIRUSES | NOVARTIS AG (CH) | 1998-09-15 | — | — | US | disclosed |