Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694160 | 0.82 | CNR2 (0.43) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL8690497 | 0.80 | CNR2 (0.42) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL8839059 | 0.80 | CNR2 (0.42) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL8691788 | 0.79 | CNR2 (0.41) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL9160266 | 0.76 | FABP4 (0.47) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL8693237 | 0.76 | RARA (0.49) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL15765977 | 0.75 | CNR2 (0.48) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL15766000 | 0.75 | TDP1 (0.51) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL566279 | 0.75 | KMT2A (0.46) | CNR2FAAHP2RX7KMT2AMEN1 | |
| SCHEMBL8691704 | 0.73 | CNR2 (0.47) | CNR2FAAHP2RX7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | claimed |
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | disclosed |