Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380602 | 0.78 | IDO1 (0.39) | TSHR | |
| SCHEMBL6049971 | 0.76 | TSHR (0.48) | TACR1TSHRHTR2ATAAR1 | |
| SCHEMBL8693287 | 0.76 | TSHR (0.48) | TSHRHTR2ATAAR1 | |
| SCHEMBL7129055 | 0.72 | HTR2A (0.50) | TACR1TSHRSCN4AHTR2ATAAR1 | |
| SCHEMBL8598002 | 0.69 | TSHR (0.58) | TSHRHTR2ATAAR1 | |
| SCHEMBL2782707 | 0.69 | SCN4A (0.68) | TACR1SCN4ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL448348 | 0.68 | DPP4 (0.53) | TSHRHTR2ATAAR1 | |
| SCHEMBL8784173 | 0.67 | HTR2A (0.39) | TACR1TSHRSCN4AHTR2ATAAR1 | |
| SCHEMBL585216 | 0.67 | TAAR1 (0.56) | HTR2ATAAR1 | |
| SCHEMBL4426990 | 0.67 | LMNA (0.56) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |