Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780668 | 0.81 | HTR2A (0.41) | HTR2ACES2CES1TRPA1HRH1 | |
| SCHEMBL9224142 | 0.79 | HTR2A (0.35) | HTR2ACES2CES1TRPA1HRH1 | |
| Dimethylamine SCHEMBL6838255 | 0.79 | MAPT (0.38) | HTR2AHRH1TAAR1TACR1TDP1 | |
| SCHEMBL7129055 | 0.76 | HTR2A (0.50) | HTR2AHRH1SCN4ATAAR1TACR1 | |
| SCHEMBL22042211 | 0.76 | HRH1 (0.46) | HTR2ACES2CES1TRPA1HRH1 | |
| SCHEMBL19317396 | 0.76 | CES2 (0.44) | HTR2ACES2CES1TRPA1HRH1 | |
| SCHEMBL4892666 | 0.74 | CES2 (0.42) | HTR2ACES2CES1TRPA1HRH1 | |
| SCHEMBL331173 | 0.74 | TRPA1 (0.42) | HTR2ACES2CES1TRPA1HRH1 | |
| SCHEMBL2302000 | 0.73 | ALDH1A1 (0.48) | CES2CES1CYP1A2CYP2D6PKM | |
| SCHEMBL11600373 | 0.73 | ALDH1A1 (0.48) | CES2CES1CYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856229-B2 | Method for producing cyclic carbonate | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20160145234-A1 | METHOD FOR PRODUCING CYCLIC CARBONATE | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2016-05-26 | — | — | US | disclosed |
| EP-3023418-A1 | METHOD FOR MANUFACTURING CYCLIC CARBONATE | National Institute of Advanced Industrial Science and Technology (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-0481676-B1 | Hydroxyquinolone derivatives | MERCK SHARP & DOHME (GB) | 1997-01-29 | — | — | EP | disclosed |
| US-5559125-A | NMDA AND AMPA RECEPTOR ANTAGONISTS, SCHIZOPHRENIA | MERCK, SHARP & DOHME LIMITED (GB) | 1996-09-24 | — | — | US | disclosed |
| EP-0522069-B1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES | ALLIED SIGNAL INC (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5364541-A | Method to impart coffee stain resistance to polyamide textile substrates | ALLIEDSIGNAL INC. | 1994-11-15 | — | — | US | disclosed |
| US-5359010-A | Phenoxy- or naphthyloxy-acrylic acid ester-maleic acid copolymers as antisoilants for nylon carpets or upholstery | ALLIEDSIGNAL INC. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5348962-A | Nervous system disorders; schizophrenia | MERCK SHARPE & DOHME LTD. | 1994-09-20 | — | — | US | disclosed |
| EP-0522069-A1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES. | ALLIED SIGNAL INC (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5135774-A | Using polymer protective coatings | ALLIED-SIGNAL INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5118551-A | Method to impart stain resistance to polyamide textile substrates | ALLIED-SIGNAL INC. (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0481676-A1 | Hydroxyquinolone derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-04-22 | — | — | EP | disclosed |
| WO-1991014818-A1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES | ALLIED-SIGNAL INC. (US) | 1991-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145234-A1 | METHOD FOR PRODUCING CYCLIC CARBONATE | CA7, CA2, CA4 | HTR2A 4647/4885CES2 80/4885CES1 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.