Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693113 | 0.84 | TNF (0.60) | KDM4EALDH1A1TSHRCTNNB1 | |
| SCHEMBL26694179 | 0.84 | TDP1 (0.71) | KDM4ERAB9ATDP1ALDH1A1HTT | |
| SCHEMBL151122 | 0.84 | KDM4E (0.71) | KDM4ERAB9ATDP1ALDH1A1HTT | |
| SCHEMBL29540705 | 0.84 | KDM4E (0.71) | KDM4ERAB9ATDP1ALDH1A1HTT | |
| SCHEMBL13066068 | 0.80 | KDM4E (0.70) | KDM4ERAB9ATDP1ALDH1A1HTT | |
| SCHEMBL31372463 | 0.80 | KDM4E (0.70) | KDM4ERAB9ATDP1ALDH1A1HTT | |
| SCHEMBL21647533 | 0.77 | PTGER4 (0.51) | KDM4EALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL17625299 | 0.77 | FOLH1 (0.62) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3679623 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1TSHRHPGDMEN1 | |
| SCHEMBL21647636 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1TSHRHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |