Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.57 |
| ▸ | ACACA | Q13085 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693498 | 1.00 | ACACB (0.57) | ACACBACACAHTR2ASLC6A4LTA4H | |
| SCHEMBL4318 | 0.80 | CYP3A4 (0.54) | HTR2ASLC6A4TSHRALDH1A1HPGD | |
| SCHEMBL21533 | 0.80 | CYP3A4 (0.54) | HTR2ASLC6A4TSHRALDH1A1HPGD | |
| SCHEMBL6133 | 0.80 | CYP3A4 (0.54) | HTR2ASLC6A4TSHRALDH1A1HPGD | |
| SCHEMBL12747746 | 0.79 | ACACB (0.53) | ACACBACACASLC6A4LTA4HALDH1A1 | |
| SCHEMBL172607 | 0.79 | LTA4H (0.57) | ACACBACACALTA4HTSHRNR1H2 | |
| SCHEMBL25969457 | 0.79 | LTA4H (0.57) | ACACBACACALTA4HTSHRALDH1A1 | |
| Methane SCHEMBL28682583 | 0.78 | CYP3A4 (0.52) | HTR2ASLC6A4TSHRALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28141900 | 0.78 | KMT2A (0.56) | HTR2ASLC6A4TSHRALDH1A1HPGD | |
| SCHEMBL327954 | 0.77 | CA1 (0.56) | ACACBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783593-A | FUNGICIDE; ANTICHOLESTEROL AGENT | ABBOTT LABORATORIES (US) | 1998-07-21 | — | — | US | disclosed |
| WO-1996034850-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |