Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 2/20 | 0.50 |
| ▸ | ACACA | Q13085 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419454 | 0.94 | ACACB (0.58) | LTA4HTSHRMAOAACACBACACA | |
| Diphenylether SCHEMBL28334518 | 0.93 | LTA4H (0.60) | LTA4HTSHRMAOAACACBACACA | |
| SCHEMBL15849015 | 0.90 | ALDH1A1 (0.48) | TSHRMAOAFNTAFNTBMEN1 | |
| SCHEMBL4366979 | 0.90 | ALDH1A1 (0.48) | TSHRMAOAFNTAFNTBMEN1 | |
| Diphenylether SCHEMBL27288324 | 0.89 | HTT (0.52) | LTA4HTSHRMAOAACACBACACA | |
| SCHEMBL25969457 | 0.86 | LTA4H (0.57) | LTA4HTSHRMAOAACACBACACA | |
| SCHEMBL21120679 | 0.84 | FNTA (0.51) | TSHRFNTAFNTBPTGS1MEN1 | |
| Bicarbonate SCHEMBL9555855 | 0.84 | RAB9A (0.50) | ACACBACACASRD5A2FNTAFNTB | |
| SCHEMBL11858946 | 0.84 | RXRA (0.63) | MAOAACACBNPC1RAB9A | |
| SCHEMBL18805968 | 0.83 | ALDH1A1 (0.46) | TSHRMAOAACACBACACAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4922010-A | Processes for preparing 2-substituted propionic acid and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | claimed |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| WO-2024059107-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-3775111-B1 | DIARYL ETHERS AS FUEL MARKERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-11814338-B2 | Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators | REATA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814338-B2 | Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators | REATA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11806335-B2 | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | Lilac Therapeutics, Inc. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11806335-B2 | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | Lilac Therapeutics, Inc. (US) | 2023-11-07 | — | — | US | disclosed |
| US-7166603-B2 | Dihydropyrimidone inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20070015797-A1 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | CHENG PETER T | 2007-01-18 | — | — | US | disclosed |
| US-7157461-B2 | Substituted dihydropyrimidine inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157461-B2 | Substituted dihydropyrimidine inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-02 | — | — | US | disclosed |
| WO-2005068437-A1 | 2, 4 - DIAMINOPYRIMIDINES AND THEIR USE FOR INDUCING CARDIOMYOGENESIS | NOVARTIS AG (CH) | 2005-07-28 | — | — | WO | disclosed |
| EP-0294220-B1 | Photopolymerizable composition | HITACHI CHEMICAL CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5034429-A | An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film | HITACHI CHEMICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4922010-A | Processes for preparing 2-substituted propionic acid and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0294220-A2 | Photopolymerizable composition | Hitachi Chemical Co., Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4066707-A | METHOD FOR MANUFACTURE OF DIPHENOLS AND MONOALKYL ETHERS OF DIPHENOLS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11806335-B2 | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | UGDH, PGD, PNPO | LTA4H 690/4885TSHR 2776/4885MAOA 75/4885 |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | LTA4H 3150/4885TSHR 4388/4885MAOA 850/4885 |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | UACA, HRAS, MYLK | LTA4H 3110/4885TSHR 3628/4885MAOA 2392/4885 |
| US-11814338-B2 | Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators | GPX4, MPO, GPX1 | LTA4H 272/4885TSHR 3603/4885MAOA 1198/4885 |
| US-20070015797-A1 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | GPR119, LIPC, ACACA | LTA4H 3219/4885TSHR 780/4885MAOA 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.