Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696774 | 0.75 | NPC1 (0.46) | PDE3BPDE3AMEN1KMT2ARAB9A | |
| SCHEMBL8695782 | 0.75 | HTT (0.40) | PDE3BPDE3ALMNAMAPTL3MBTL1 | |
| SCHEMBL8689877 | 0.74 | HTT (0.40) | PDE3BPDE3ALMNAMAPTL3MBTL1 | |
| SCHEMBL15884482 | 0.73 | TEAD2 (0.44) | TEAD2MEN1KMT2AADORA3ADORA2A | |
| SCHEMBL20028207 | 0.73 | TSHR (0.50) | PDE3BPDE3ARAB9ANPC1ADORA3 | |
| SCHEMBL8697260 | 0.73 | PDE3B (0.50) | PDE3BPDE3AMEN1KMT2ARAB9A | |
| SCHEMBL8692878 | 0.73 | HTT (0.43) | PDE3BPDE3ALMNAL3MBTL1HTT | |
| SCHEMBL8691319 | 0.72 | CYP19A1 (0.47) | PDE3BPDE3AKMT2ALMNAMAPT | |
| SCHEMBL15884305 | 0.71 | TEAD2 (0.46) | TEAD2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8690998 | 0.70 | CNR2 (0.38) | KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |