Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879237 | 0.79 | AGTR1 (0.39) | NPC1LMNAAGTR1KMT2ASMN1; SMN2 | |
| SCHEMBL4719726 | 0.78 | LMNA (0.43) | NPC1LMNAKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8697260 | 0.77 | PDE3B (0.50) | NPC1LMNAPDE3BPDE3AKMT2A | |
| SCHEMBL8692878 | 0.77 | HTT (0.43) | LMNAPDE3BPDE3ASMN1; SMN2HTT | |
| SCHEMBL9041592 | 0.77 | AGTR1 (0.81) | AGTR1 | |
| SCHEMBL8693592 | 0.76 | HTT (0.42) | SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8694309 | 0.75 | PDE3B (0.45) | NPC1LMNAPDE3BPDE3AKMT2A | |
| SCHEMBL8695782 | 0.75 | HTT (0.40) | LMNAPDE3BPDE3ASMN1; SMN2MAPT | |
| SCHEMBL8695084 | 0.75 | EGFR (0.44) | NPC1LMNAPDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL4721483 | 0.74 | LMNA (0.49) | NPC1LMNAKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| US-5750562-A | ANTITUMOR AGENTS; WATER SOLUBLE; SIDE EFFECT REDUCTION | INDENA S.P.A. (IT) | 1998-05-12 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |