Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79230 | 0.81 | ALOX5AP (0.41) | ALOX5APFEN1RXRARXRBRXRG | |
| SCHEMBL81656 | 0.81 | S1PR1 (0.44) | ALOX5APFEN1RXRARXRBRXRG | |
| SCHEMBL31692917 | 0.77 | ALOX5AP (0.47) | ALOX5APFEN1S1PR1PDE3BPDE3A | |
| SCHEMBL22353060 | 0.77 | S1PR1 (0.56) | RXRARXRBRXRGS1PR1 | |
| SCHEMBL30349000 | 0.74 | CCNT1 (0.36) | ALOX5APFEN1S1PR1PDE3A | |
| SCHEMBL28961384 | 0.74 | CCNT1 (0.40) | S1PR1 | |
| SCHEMBL31693045 | 0.73 | ALOX5AP (0.42) | ALOX5APFEN1RXRARXRBRXRG | |
| SCHEMBL25612367 | 0.69 | GAA (0.33) | ALOX5APFEN1S1PR1PDE3A | |
| SCHEMBL25612189 | 0.69 | CALM1 (0.36) | S1PR1 | |
| SCHEMBL30349123 | 0.69 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129361-B2 | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HLA-B, HLA-A, HLA-C | ALOX5AP 603/4885FEN1 4069/4885RXRA 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.