Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612189 | 0.94 | CALM1 (0.36) | SMN1; SMN2LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL30349000 | 0.89 | CCNT1 (0.36) | GAASMN1; SMN2LMNAS1PR2S1PR1 | |
| SCHEMBL25612432 | 0.86 | MAPT (0.35) | SMN1; SMN2LMNAMAPK1MEN1KMT2A | |
| SCHEMBL25612301 | 0.86 | MAPT (0.40) | GAASMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL28961384 | 0.84 | CCNT1 (0.40) | SMN1; SMN2LMNAS1PR2S1PR1S1PR3 | |
| SCHEMBL25612352 | 0.83 | L3MBTL1 (0.35) | SMN1; SMN2S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL25612357 | 0.78 | WDR5 (0.31) | CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL28917408 | 0.76 | MAPT (0.41) | GAASMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL28917329 | 0.76 | CCNT1 (0.37) | SMN1; SMN2LMNAMAPK1MEN1KMT2A | |
| SCHEMBL30349123 | 0.76 | MAPT (0.41) | GAASMN1; SMN2LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | CYP8B1, HSD11B1, HSD11B2 | GAA 1585/4885SMN1; SMN2 3552/4885LMNA 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.