Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28900480 | 0.80 | FOLH1 (0.36) | SRCADAMTS4FOLH1APPCYP3A4 | |
| SCHEMBL7678184 | 0.76 | TDP1 (0.40) | SRCCYP2C9CYP2C19CA1CA2 | |
| SCHEMBL457188 | 0.76 | TDP1 (0.40) | SRCCYP2C9CYP2C19CA1CA2 | |
| SCHEMBL4131151 | 0.76 | CTSS (0.41) | APPCA2KMT2AALDH1A1NPC1 | |
| SCHEMBL28664391 | 0.73 | SRC (0.38) | SRCAPPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1586226 | 0.68 | CYP2D6 (0.39) | KMT2AALDH1A1GAATDP1CNR1 | |
| SCHEMBL38173 | 0.67 | FOLH1 (0.51) | FOLH1CA1CA2NAALAD2KMT2A | |
| SCHEMBL38174 | 0.67 | FOLH1 (0.51) | FOLH1CA1CA2NAALAD2KMT2A | |
| SCHEMBL7564093 | 0.66 | SRC (0.39) | SRCCYP3A4CYP2C9CYP2C19CA1 | |
| SCHEMBL5521344 | 0.66 | ESR1 (0.46) | CYP3A4CYP2C9CYP2C19TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333536-A | Ss-arrestin effectors and compositions and methods of use thereof | TREVENA INC | 2012-01-25 | — | — | CN | claimed |
| CN-102333536-A | Ss-arrestin effectors and compositions and methods of use thereof | TREVENA INC | 2012-01-25 | — | — | CN | disclosed |
| US-5710129-A | Inhibitors of SH2-mediated processes | ARIAD PHARMACEUTICALS, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1997031016-A2 | NEW INHIBITORS OF SH2-MEDIATED PROCESSES | ARIAD PHARMACEUTICALS, INC. (US) | 1997-08-28 | — | — | WO | disclosed |