Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 7/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538911 | 0.84 | CES2 (0.43) | SRCFBP1TDP1ALDH1A1CES2 | |
| SCHEMBL8838581 | 0.73 | ESR1 (0.42) | SRCEGFRFBP1TDP1ALDH1A1 | |
| SCHEMBL4615004 | 0.73 | SRC (0.45) | SRCCPT1BTDP1ALDH1A1GAA | |
| SCHEMBL6054379 | 0.71 | SRC (0.48) | SRCCPT1BTDP1ALDH1A1GAA | |
| SCHEMBL5053923 | 0.71 | IDO1 (0.44) | TDP1ALDH1A1GAAKMT2AESR1 | |
| SCHEMBL4543337 | 0.69 | ESR1 (0.50) | EGFRFBP1TDP1ESR1ESR2 | |
| SCHEMBL19433875 | 0.69 | SRC (0.42) | SRCCPT1BTDP1ALDH1A1GAA | |
| SCHEMBL11511443 | 0.69 | EGFR (0.39) | SRCEGFRFBP1TDP1ALDH1A1 | |
| SCHEMBL9577440 | 0.69 | ESR1 (0.50) | SRCCPT1BTDP1GAAESR1 | |
| SCHEMBL74691 | 0.69 | SRC (0.48) | SRCTDP1ALDH1A1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002031189-A2 | MODEL SYSTEM FOR THE VIVO STUDY OF APOPTOSIS | EIRX THERAPEUTIC LIMITED (IE) | 2002-04-18 | — | — | WO | disclosed |