Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695744 | 0.97 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8693570 | 0.94 | MTNR1A (0.69) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8690242 | 0.90 | MTNR1A (0.68) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8693684 | 0.88 | MTNR1A (0.61) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8690976 | 0.84 | MEN1 (0.65) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6247364 | 0.83 | MTNR1A (0.86) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8693024 | 0.83 | MTNR1A (0.65) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8690045 | 0.82 | MTNR1A (0.70) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8689984 | 0.81 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL5337584 | 0.81 | EPHX2 (0.54) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |