Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693684 | 0.96 | MTNR1A (0.61) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL8690242 | 0.90 | MTNR1A (0.68) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL8695744 | 0.88 | MTNR1A (0.64) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL8693570 | 0.86 | MTNR1A (0.69) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8694576 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8693483 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8693941 | 0.81 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2HTR2CHTR2B | |
| SCHEMBL8017007 | 0.81 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL2752183 | 0.81 | EPHX1 (0.67) | MEN1KMT2ASMN1; SMN2EPHX2POLB | |
| SCHEMBL2751915 | 0.80 | SIGMAR1 (0.67) | MEN1KMT2ASMN1; SMN2EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |