Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574501 | 1.00 | MAOB (0.46) | MAOBMAOAPARP1PARP10GRM5 | |
| SCHEMBL29758931 | 0.87 | MAOB (0.58) | MAOBMAOAGRM5NPC1RAB9A | |
| SCHEMBL1452071 | 0.87 | MAOB (0.58) | MAOBMAOAGRM5NPC1RAB9A | |
| SCHEMBL12217136 | 0.83 | CYP19A1 (0.49) | MAOBMAOAGRM5MAPTNPC1 | |
| SCHEMBL69688 | 0.83 | TERT (0.46) | MAOBMAOAPARP1PARP10MAPT | |
| SCHEMBL13538433 | 0.80 | PIK3CA (0.40) | PARP1PARP10MAPTPIK3CAPIK3CB | |
| SCHEMBL17362041 | 0.78 | MAOB (0.53) | MAOBMAOAGRM5NPC1RAB9A | |
| SCHEMBL27957836 | 0.78 | MAOB (0.45) | MAOBMAOAGRM5NPC1RAB9A | |
| SCHEMBL1450607 | 0.78 | MAOB (0.47) | MAOBMAOAPARP1PARP10GRM5 | |
| SCHEMBL30953601 | 0.78 | MAOB (0.47) | MAOBMAOAPARP1PARP10GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346586-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | ARTAX BIOPHARMA INC (US) | 2025-11-13 | — | — | US | disclosed |
| US-12319675-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | ARTAX BIOPHARMA INC. (US) | 2025-06-03 | — | — | US | disclosed |
| US-20240199592-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | ARTAX BIOPHARMA INC. | 2024-06-20 | — | — | US | disclosed |
| CN-117304157-A | Chromene derivatives as inhibitors of TCR-NCK interactions | 阿塔克斯生物制药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-11807633-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | ARTAX BIOPHARMA INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807633-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | ARTAX BIOPHARMA INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807633-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | ARTAX BIOPHARMA INC. (US) | 2023-11-07 | — | — | US | disclosed |
| CN-112189009-B | Chromene derivatives as inhibitors of TCR-NCK interactions | 阿塔克斯生物制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-20220081429-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | ARTAX BIOPHARMA INC. | 2022-03-17 | — | — | US | disclosed |
| US-11008310-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | ARTAX BIOPHARMA INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-20090087575-A1 | INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042573-A1 | Ink composition | FUJIFILM Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042563-A1 | Photocurable coating composition, and overprint and process for producing same | FUJIFILM Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-20090081421-A1 | PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20080239045-A1 | INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080239045-A1 | INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1975210-A1 | Ink set for inkjet recording and inkjet recording method | FUJIFILM Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-20080182031-A1 | Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound | FUJIFILM CORPORATION (JP) | 2008-07-31 | — | — | US | disclosed |
| US-20080182031-A1 | Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound | FUJIFILM CORPORATION (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1944173-A1 | Ink composition and inkjet recording method using the same | FUJIFILM Corporation (JP) | 2008-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12319675-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
| US-20240199592-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
| US-20220081429-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
| US-11807633-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
| US-20250346586-A1 | CHROMENE DERIVATIVES AS INHIBITORS OF TCR-NCK INTERACTION | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
| US-20090087575-A1 | INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME | RB1, IK, NOX1 | MAOB 202/4885MAOA 415/4885PARP1 2522/4885 |
| US-11008310-B2 | Chromene derivatives as inhibitors of TCR-Nck interaction | NCK1, NCKAP1, NCKAP1L | MAOB 4744/4885MAOA 4786/4885PARP1 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.