Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693057 | 0.91 | SLC6A4 (0.55) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL8692181 | 0.84 | RAB9A (0.43) | CYP2D6RAB9AACACBNPC1 | |
| SCHEMBL8697115 | 0.77 | ACACB (0.44) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL7925062 | 0.73 | CYP2D6 (0.50) | SLC6A4TAAR1CYP2D6CYP3A4RAB9A | |
| SCHEMBL5018909 | 0.72 | TAAR1 (0.59) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL11193009 | 0.72 | ALDH1A1 (0.46) | SLC6A4TAAR1CYP2D6CYP3A4RAB9A | |
| SCHEMBL8692093 | 0.71 | CYP3A4 (0.51) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL8695531 | 0.71 | NPC1 (0.38) | RAB9AALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL22885190 | 0.69 | TAAR1 (0.81) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL98038 | 0.69 | TAAR1 (0.56) | SLC6A4TAAR1CYP2D6CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | claimed |
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5670531-A | ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-09-23 | — | — | US | disclosed |