Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690384 | 0.92 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2POLBALDH1A1 | |
| SCHEMBL17785106 | 0.89 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2ALDH1A1LMNA | |
| SCHEMBL8695135 | 0.89 | POLB (0.57) | MTNR1AMTNR1BNQO2POLBALDH1A1 | |
| SCHEMBL8695023 | 0.88 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2ALDH1A1RAB9A | |
| SCHEMBL8886379 | 0.86 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ALDH1A1RAB9A | |
| SCHEMBL31622920 | 0.86 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ALDH1A1RAB9A | |
| SCHEMBL8006826 | 0.84 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2ALDH1A1LMNA | |
| SCHEMBL4137010 | 0.82 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2ALDH1A1LMNA | |
| SCHEMBL8690388 | 0.81 | MAPT (0.53) | MTNR1AMTNR1BNQO2POLBALDH1A1 | |
| SCHEMBL7018941 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |