Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695135 | 0.92 | POLB (0.57) | MAPTTDP1POLBKDM4EMTNR1A | |
| SCHEMBL8690384 | 0.90 | MTNR1A (0.64) | POLBMTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL8695223 | 0.90 | MTNR1A (0.56) | MAPTTDP1KDM4EMTNR1AMTNR1B | |
| SCHEMBL204937 | 0.83 | MAPT (0.67) | MAPTTDP1KDM4ELCKALDH1A1 | |
| SCHEMBL8019040 | 0.83 | MTNR1A (0.55) | MAPTTDP1KDM4EMTNR1AMTNR1B | |
| SCHEMBL8695136 | 0.81 | MTNR1A (0.67) | POLBMTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL25320268 | 0.81 | MTNR1A (0.66) | MAPTTDP1KDM4EMTNR1AMTNR1B | |
| SCHEMBL4131741 | 0.80 | PIN1 (0.54) | MAPTTDP1KDM4EMTNR1AMTNR1B | |
| SCHEMBL8006826 | 0.79 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2ALDH1A1TSHR | |
| SCHEMBL23188008 | 0.78 | CYP11B1 (0.57) | MAPTTDP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |