SCHEMBL8695311

SCHEMBL8695311

CC(C)(C)c1ccccc1OC[C@@H]1CO1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
GLA P06280 1/20 0.65
TDP1 Q9NUW8 1/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TP53 P04637 3/20 0.49
TSHR P16473 3/20 0.49
MAPT P10636 3/20 0.49
HPGD P15428 2/20 0.49
CYP1A2 P05177 2/20 0.49
HIF1A Q16665 2/20 0.49
PPARG P37231 1/20 0.49
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
CYP3A4 P08684 1/20 0.46
NISCH Q9Y2I1 1/20 0.44
RBP4 P02753 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80170 1.00 ALDH1A1 (0.65) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL30033688 1.00 ALDH1A1 (0.65) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL8695675 1.00 ALDH1A1 (0.65) ALDH1A1GLATDP1MEN1KMT2A
Tert-Butylbenzene SCHEMBL28083134 0.93 ALDH1A1 (0.56) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL241150 0.90 ALDH1A1 (0.65) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL2905738 0.90 ALDH1A1 (0.65) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL8159336 0.86 ALDH1A1 (0.64) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL16828356 0.86 ALDH1A1 (0.55) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL11090576 0.86 ALDH1A1 (0.59) ALDH1A1GLATDP1MEN1KMT2A
SCHEMBL10629817 0.86 ALDH1A1 (0.59) ALDH1A1GLATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998003485-A1 PHENOXYPROPANOLAMINES HAVING β3-ADRENERGIC ANTAGONIST ACTIVITY SANOFI (FR) 1998-01-29 WO disclosed