Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8699857 | 0.92 | F2 (0.44) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8697603 | 0.89 | HTR6 (0.45) | F2HTR6CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL8696332 | 0.89 | HTR6 (0.43) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8696128 | 0.89 | F2 (0.44) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8694486 | 0.87 | F2 (0.46) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8695379 | 0.87 | F2 (0.60) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8695301 | 0.86 | HTR6 (0.52) | F2HTR6CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL8696200 | 0.82 | F2 (0.41) | F2HTR6CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL8698561 | 0.82 | HTR6 (0.41) | F2HTR6CTRCPRSS2F10 | |
| SCHEMBL8696257 | 0.80 | F2 (0.44) | F2HTR6CTRCPRSS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | claimed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |