Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 17/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8696200 | 0.93 | F2 (0.41) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8696257 | 0.91 | F2 (0.44) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8696128 | 0.91 | F2 (0.44) | HTR6F2PRSS2F10CTRC | |
| Hydrochloric Acid SCHEMBL8696332 | 0.91 | HTR6 (0.43) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8695388 | 0.89 | F2 (0.44) | HTR6F2PRSS2F10CTRC | |
| Hydrochloric Acid SCHEMBL8694941 | 0.89 | F2 (0.39) | HTR6F2PRSS2F10CTRC | |
| Hydrochloric Acid SCHEMBL8696326 | 0.89 | HTR6 (0.36) | HTR6F2PRSS2F10CTRC | |
| Hydrochloric Acid SCHEMBL8699857 | 0.88 | F2 (0.44) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8697964 | 0.88 | HTR6 (0.41) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8695301 | 0.88 | HTR6 (0.52) | HTR6F2PRSS2F10CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | claimed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |