Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696801 | 0.95 | ALDH1A1 (0.43) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8693755 | 0.91 | EPHX1 (0.48) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8697491 | 0.91 | EPHX1 (0.48) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8696424 | 0.90 | SMN1; SMN2 (0.40) | EPHX1ALDH1A1HTT | |
| SCHEMBL8694654 | 0.88 | KDM4E (0.39) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8696100 | 0.86 | EPHX1 (0.52) | EPHX1ALDH1A1HTTPTPN1EPHX2 | |
| SCHEMBL8693610 | 0.86 | HCAR2 (0.43) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8695491 | 0.86 | HCAR2 (0.47) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8695984 | 0.86 | EPHX1 (0.42) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL8693503 | 0.84 | HCAR2 (0.47) | EPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |