Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696177 | 0.96 | ALDH1A1 (0.46) | EPHX1ALDH1A1HTTPOLBHPGD | |
| SCHEMBL8695495 | 0.91 | L3MBTL1 (0.45) | EPHX1ALDH1A1HTTPOLBCREBBP | |
| SCHEMBL8696777 | 0.89 | POLB (0.44) | EPHX1ALDH1A1HTTPOLBHPGD | |
| SCHEMBL8696191 | 0.89 | EPHX1 (0.47) | EPHX1ALDH1A1HTTPOLBCREBBP | |
| SCHEMBL8695486 | 0.86 | EPHX1 (0.49) | EPHX1ALDH1A1HTTPTPN1GHSR | |
| SCHEMBL8697491 | 0.85 | EPHX1 (0.48) | EPHX1ALDH1A1HTTPTPN1EPHX2 | |
| SCHEMBL8693755 | 0.85 | EPHX1 (0.48) | EPHX1ALDH1A1HTTPTPN1EPHX2 | |
| SCHEMBL8692678 | 0.85 | HTT (0.46) | ALDH1A1HTTPOLBHPGDCREBBP | |
| SCHEMBL8696343 | 0.84 | ALDH1A1 (0.47) | EPHX1ALDH1A1HTTPOLBCREBBP | |
| SCHEMBL8842704 | 0.82 | POLB (0.46) | EPHX1ALDH1A1HTTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |