Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.32 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8694847 | 0.89 | ICMT (0.33) | ALOX5MCHR1CSF1R | |
| SCHEMBL8696318 | 0.87 | ALOX5 (0.33) | ALOX5HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8698167 | 0.83 | NR3C2 (0.39) | ALOX5HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8700996 | 0.83 | ALOX5 (0.44) | ALOX5HTR1AMCHR1NR3C2 | |
| SCHEMBL8694707 | 0.79 | ALOX5 (0.44) | ALOX5HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8701075 | 0.77 | ALOX5 (0.49) | ALOX5MCHR1CSF1RNR3C2 | |
| Hydrochloric Acid SCHEMBL8700999 | 0.77 | ALOX5 (0.48) | ALOX5MCHR1CSF1RNR3C2 | |
| Hydrochloric Acid SCHEMBL8697471 | 0.77 | ALOX5 (0.44) | ALOX5MCHR1CSF1RNR3C2 | |
| SCHEMBL8698238 | 0.76 | ALOX5 (0.44) | ALOX5HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8701027 | 0.76 | ALOX5 (0.46) | ALOX5MCHR1GPBAR1CSF1RNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753682-A | Imidazole lipoxygenase inhibitors | PFIZER INC. (US) | 1998-05-19 | — | — | US | claimed |
| US-5753682-A | Imidazole lipoxygenase inhibitors | PFIZER INC. (US) | 1998-05-19 | — | — | US | disclosed |