Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584188 | 0.82 | MTNR1A (0.50) | SLC6A2SLC6A4SLC6A3SOS1KDM1A | |
| SCHEMBL1475516 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4KCNH2SLC6A3HTR2A | |
| SCHEMBL6583557 | 0.76 | SLC6A2 (0.41) | SLC6A2SLC6A4KCNH2SLC6A3PARP1 | |
| SCHEMBL3127041 | 0.75 | HTR2A (0.50) | SLC6A2SLC6A4KCNH2SLC6A3HTR2A | |
| SCHEMBL12748450 | 0.74 | KCNH2 (0.45) | SLC6A2SLC6A4KCNH2SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL1477630 | 0.73 | KCNH2 (0.44) | SLC6A2SLC6A4KCNH2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7836912 | 0.72 | TACR1 (0.57) | SLC6A3HTR2AHTR2CHRH1 | |
| SCHEMBL700880 | 0.71 | MTNR1A (0.56) | KDM1AMAOAMAOB | |
| SCHEMBL614437 | 0.71 | HTR1A (0.46) | SLC6A2SLC6A4KCNH2SLC6A3HTR2C | |
| SCHEMBL13146592 | 0.70 | HTR2A (0.46) | SLC6A2SLC6A4KCNH2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767116-A | TREATING PSYCHOSES | KNOLL ATKIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |