Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CDK4 | P11802 | 2/20 | 0.61 |
| ▸ | CCND1 | P24385 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838803 | 0.92 | LMNA (0.76) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7853851 | 0.88 | MAPT (0.66) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7850581 | 0.88 | KMT2A (0.65) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7846817 | 0.88 | MAPT (0.78) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7847723 | 0.85 | POLB (0.64) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL6643764 | 0.85 | MEN1 (0.76) | LMNASMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7853896 | 0.84 | TRPV1 (0.65) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7852416 | 0.84 | MAPT (0.66) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7847028 | 0.84 | MAPT (0.80) | LMNASMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL7848062 | 0.83 | MAPT (0.65) | LMNASMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |