Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075691 | 0.80 | HTT (0.56) | MEN1KMT2ADPP4DPP7DPP8 | |
| SCHEMBL9075694 | 0.80 | HTT (0.56) | MEN1KMT2ADPP4DPP7DPP8 | |
| SCHEMBL4154315 | 0.80 | ALDH1A1 (0.52) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4741712 | 0.80 | ALDH1A1 (0.52) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL8246719 | 0.80 | ALDH1A1 (0.52) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL31369645 | 0.79 | SLC1A1 (0.39) | LTA4HGPR88MEN1KMT2A | |
| SCHEMBL31370273 | 0.79 | SLC1A1 (0.39) | LTA4HGPR88MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4741714 | 0.79 | ALDH1A1 (0.51) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4741718 | 0.79 | ALDH1A1 (0.51) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11036648 | 0.77 | SLC1A1 (0.60) | LTA4HMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |