Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGAT1 | P26572 | 1/20 | 0.38 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CBX7 | O95931 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693444 | 1.00 | TGM2 (0.42) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL8697033 | 1.00 | TGM2 (0.42) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL8694315 | 0.84 | CHRM1 (0.46) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL7426938 | 0.75 | MAPT (0.55) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL7478070 | 0.73 | NSD2 (0.42) | TGM2CES1MAPT | |
| SCHEMBL7483462 | 0.73 | NSD2 (0.42) | TGM2CES1MAPT | |
| SCHEMBL7472238 | 0.73 | NSD2 (0.42) | TGM2CES1MAPT | |
| SCHEMBL8880980 | 0.70 | MDM2 (0.40) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL8880758 | 0.69 | MAOB (0.41) | TGM2CES1IDO1PGRTDO2 | |
| SCHEMBL8880752 | 0.69 | MAOB (0.41) | TGM2CES1IDO1PGRTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798365-A | VIRICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |