Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MGAT1 | P26572 | 1/20 | 0.36 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880758 | 0.90 | MAOB (0.41) | MDM2MAOBTGM2CES1PGR | |
| SCHEMBL8880752 | 0.90 | MAOB (0.41) | MDM2MAOBTGM2CES1PGR | |
| SCHEMBL8296633 | 0.82 | MAOB (0.47) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8296634 | 0.82 | MAOB (0.47) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8881059 | 0.80 | TGM2 (0.41) | MDM2MAOBTGM2CES1PGR | |
| SCHEMBL8304351 | 0.77 | TGM2 (0.46) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8881911 | 0.77 | TGM2 (0.46) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8304353 | 0.77 | TGM2 (0.46) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8880831 | 0.77 | TGM2 (0.46) | MAOBTGM2CES1PGRMAPT | |
| SCHEMBL8303880 | 0.74 | CHRM1 (0.42) | TGM2CES1PGRIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602146-A | ANTIVIRAL AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |