SCHEMBL869660

SCHEMBL869660

CCCCC(C)(C)c1cccc2c1C(=O)NC2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GSK3B P49841 2/20 0.36
KCNA5 P22460 1/20 0.36
PARP1 P09874 1/20 0.35
CASP3 P42574 2/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
STK10 O94804 5/20 0.34
SLK Q9H2G2 5/20 0.34
GSK3A P49840 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
ALOX12 P18054 1/20 0.33
CES1 P23141 1/20 0.33
CASP2 P42575 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2156113 0.77 KDM4E (0.47) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL8827920 0.74 KDM4E (0.45) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL166776 0.72 ELANE (0.43) KDM4EALDH1A1HPGDGAAHSD17B10
Bicarbonate SCHEMBL23581765 0.72 KDM4E (0.50) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL29699198 0.72 ELANE (0.43) KDM4EALDH1A1HPGDGAAHSD17B10
Hydrochloric Acid SCHEMBL27668518 0.71 ELANE (0.43) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL9510827 0.71 GSK3B (0.44) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL29699286 0.71 NR1H2 (0.47) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL2508510 0.71 NR1H2 (0.47) KDM4EALDH1A1HPGDGAAHSD17B10
SCHEMBL30360556 0.71 CES1 (0.56) KDM4EALDH1A1HPGDGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2618805-B1 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION UNILEVER PLC (GB) 2016-04-27 EP claimed
US-8524203-B2 Sunscreen composite particles for UVA and UVB protection CONOPCO, INC. (US) 2013-09-03 US claimed
EP-2618805-A2 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION Unilever PLC (GB) 2013-07-31 EP claimed
CN-103209675-A Sunscreen composite particles for UVA and UVB protection UNILEVER PLC 2013-07-17 CN claimed
US-20120076741-A1 Sunscreen Composite Particles for UVA and UVB Protection CONOPCO, INC., D/B/A UNILEVER (US) 2012-03-29 US claimed
WO-2012038145-A2 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION UNILEVER PLC (GB) 2012-03-29 WO claimed
EP-2618805-B1 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION UNILEVER PLC (GB) 2016-04-27 EP disclosed
US-8524203-B2 Sunscreen composite particles for UVA and UVB protection CONOPCO, INC. (US) 2013-09-03 US disclosed
EP-2618805-A2 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION Unilever PLC (GB) 2013-07-31 EP disclosed
CN-103209675-A Sunscreen composite particles for UVA and UVB protection UNILEVER PLC 2013-07-17 CN disclosed
US-20120076741-A1 Sunscreen Composite Particles for UVA and UVB Protection CONOPCO, INC., D/B/A UNILEVER (US) 2012-03-29 US disclosed
WO-2012038145-A2 SUNSCREEN COMPOSITE PARTICLES FOR UVA AND UVB PROTECTION UNILEVER PLC (GB) 2012-03-29 WO disclosed
WO-2011054628-A1 ENHANCED PHOTO PROTECTION UNILEVER PLC (GB) 2011-05-12 WO disclosed
US-20110104082-A1 ENHANCED PHOTO PROTECTION CONOPCO, INC., D/B/A UNILEVER (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110104082-A1 ENHANCED PHOTO PROTECTION ERCC1, PCNA, CUTA KDM4E 1475/4885ALDH1A1 902/4885HPGD 322/4885
US-20120076741-A1 Sunscreen Composite Particles for UVA and UVB Protection SUN2, VKORC1L1, VKORC1 KDM4E 2286/4885ALDH1A1 876/4885HPGD 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.