Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692506 | 0.96 | TEAD2 (0.39) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8693972 | 0.93 | ALDH1A1 (0.42) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8694568 | 0.91 | TEAD2 (0.39) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8696011 | 0.90 | KDM4E (0.40) | TEAD2ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8696060 | 0.87 | TEAD2 (0.37) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8698769 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2FOS | |
| SCHEMBL8693715 | 0.85 | TEAD2 (0.40) | TEAD2KDM4EKMT2ASMN1; SMN2HPGD | |
| SCHEMBL8694190 | 0.83 | KDM4E (0.41) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8693986 | 0.82 | ALDH1A1 (0.43) | TEAD2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8696856 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |