Fluorescein

Fluorescein

SCHEMBL8697200

Nc1ccc(N)cc1.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.87
MAPT P10636 4/20 0.87
MEN1 O00255 4/20 0.87
KMT2A Q03164 4/20 0.87
TDP1 Q9NUW8 3/20 0.87
HTT P42858 2/20 0.87
HPGD P15428 2/20 0.87
RECQL P46063 2/20 0.87
BLM P54132 2/20 0.87
PRMT1 Q99873 2/20 0.87
ACE2 Q9BYF1 2/20 0.87
CYP2C19 P33261 1/20 0.87
SMAD3 P84022 1/20 0.87
LMNA P02545 3/20 0.61
POLB P06746 2/20 0.61
GPR55 Q9Y2T6 2/20 0.61
ALOX12 P18054 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ALDH1A1 P00352 3/20 0.56
USP2 O75604 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12203251 0.96 FTO (0.85) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL27087693 0.93 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL1198361 0.93 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29388667 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3645090 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL30272223 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL16533 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 0.93 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL5578117 0.93 FTO (0.75) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL28297857 0.92 FTO (0.92) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705649-A USING (7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO ALKANOIC ACID DERIVATIVE FLUORESCENT DYES PROMEGA CORPORATION (US) 1998-01-06 US disclosed
EP-0558658-A4 1994-08-31 EP disclosed
EP-0558658-A1 PROTEIN STAINING COMPOSITIONS AND METHODS PROMEGA CORPORATION (US) 1993-09-08 EP disclosed
WO-1992008689-A1 PROTEIN STAINING COMPOSITIONS AND METHODS PROMEGA CORPORATION (US) 1992-05-29 WO disclosed