Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 7/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697822 | 0.87 | PSMB8 (0.63) | PSMB8KEAP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8697342 | 0.85 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1KMT2A | |
| SCHEMBL8697415 | 0.85 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1KMT2A | |
| SCHEMBL118689 | 0.80 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8698103 | 0.79 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL16150847 | 0.79 | PSMB8 (0.61) | PSMB8KEAP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8701858 | 0.75 | PSMB8 (0.54) | PSMB8KEAP1KDM4EALDH1A1KMT2A | |
| SCHEMBL1094167 | 0.75 | PSMB8 (0.65) | PSMB8KEAP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8704890 | 0.74 | PSMB8 (0.53) | PSMB8KEAP1KDM4EALDH1A1KMT2A | |
| SCHEMBL8698800 | 0.73 | PSMB8 (0.52) | PSMB8KEAP1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |