Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 7/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697822 | 0.87 | PSMB8 (0.63) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8697415 | 0.85 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1SRD5A2 | |
| SCHEMBL8697214 | 0.85 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL17260664 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1GAALMNACREBBP | |
| SCHEMBL8701858 | 0.81 | PSMB8 (0.54) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL118689 | 0.80 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8698103 | 0.79 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL779231 | 0.79 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL1094167 | 0.75 | PSMB8 (0.65) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8704890 | 0.74 | PSMB8 (0.53) | PSMB8KEAP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |