Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 6/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697415 | 0.87 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8697822 | 0.86 | PSMB8 (0.63) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8697214 | 0.79 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8697342 | 0.79 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL14553955 | 0.78 | PSMB8 (0.70) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL118689 | 0.76 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL799525 | 0.76 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL31389040 | 0.76 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8701858 | 0.75 | PSMB8 (0.54) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL1094185 | 0.74 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |