Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700104 | 0.88 | CYP19A1 (0.45) | CYP19A1 | |
| SCHEMBL8702199 | 0.87 | CYP19A1 (0.45) | CYP19A1RAB9AAR | |
| SCHEMBL8696804 | 0.87 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL8700017 | 0.83 | CYP19A1 (0.42) | CYP19A1AR | |
| SCHEMBL8697427 | 0.82 | CYP19A1 (0.42) | CYP19A1AR | |
| SCHEMBL8702831 | 0.81 | CYP19A1 (0.66) | CYP19A1USP2RAB9A | |
| SCHEMBL8697579 | 0.73 | CYP19A1 (0.51) | CYP19A1RAB9A | |
| SCHEMBL8700003 | 0.73 | CYP19A1 (0.58) | CYP19A1RAB9A | |
| SCHEMBL8700111 | 0.72 | CYP3A4 (0.46) | CYP19A1AR | |
| SCHEMBL8697676 | 0.70 | CYP19A1 (0.48) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |