Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.73 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856641 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9294691 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293922 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL8070551 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293800 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL10652746 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9294488 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293748 | 0.99 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293406 | 0.95 | ADORA2B (0.83) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL16120975 | 0.92 | ADORA2B (0.88) | ADORA2BLMNAMAPK1RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710272-A | INCREASING CEREBRAL BLOOD FLOW | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0435152-B1 | Process for the enantioselective preparation of (omega-1)-hydroxyalkylxanthines | HOECHST AG (DE) | 1996-11-13 | — | — | EP | disclosed |
| US-5472873-A | Rhodotorula rubra useful in a process for the preparation of (ω-1)-hydroxyalkylxanthines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-05 | — | — | US | disclosed |
| US-5310666-A | Vascular disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| EP-0435152-A2 | Process for the enantioselective preparation of (omega-1)-hydroxyalkylxanthines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
| EP-0089028-B1 | THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-05-25 | — | — | EP | disclosed |
| US-4565817-A | ANTITUSSIVE AGENTS | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1986-01-21 | — | — | US | disclosed |
| EP-0089028-A1 | Theophyllin derivatives, and process for their preparation | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1983-09-21 | — | — | EP | disclosed |