Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294691 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293800 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL10652746 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL10856641 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9294488 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL8070551 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293922 | 1.00 | ADORA2B (0.78) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL8697228 | 0.99 | ADORA2B (0.81) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL9293406 | 0.94 | ADORA2B (0.83) | ADORA2BLMNAMAPK1RXFP1PDE4A | |
| SCHEMBL10985224 | 0.94 | ADORA2B (0.69) | ADORA2BLMNAMAPK1RXFP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288721-A | Substituted epoxyalkyl xanthines | CELL THERAPEUTICS, INC. (US) | 1994-02-22 | — | — | US | disclosed |