Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698002 | 0.86 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8702831 | 0.86 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8697420 | 0.86 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL3612581 | 0.86 | CFTR (0.42) | CYP19A1CYP3A4CFTRGOPC | |
| SCHEMBL8698067 | 0.83 | CYP3A4 (0.47) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL913343 | 0.80 | CYP19A1 (0.79) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL9707695 | 0.78 | CYP2C9 (0.43) | CYP19A1CFTRGOPC | |
| SCHEMBL8700104 | 0.77 | CYP19A1 (0.45) | CYP19A1CYP3A4 | |
| SCHEMBL8697676 | 0.75 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8698102 | 0.74 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |