Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204424 | 0.94 | L3MBTL1 (0.69) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL28727176 | 0.87 | KMT2A (0.58) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL13100658 | 0.86 | KMT2A (0.79) | L3MBTL1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31326036 | 0.85 | KMT2A (0.70) | L3MBTL1KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL1754734 | 0.85 | TSHR (0.53) | L3MBTL1KMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL31326025 | 0.85 | TSHR (0.53) | L3MBTL1KMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL8694320 | 0.84 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2397228 | 0.83 | L3MBTL1 (0.69) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL31326026 | 0.82 | KMT2A (0.55) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8695606 | 0.82 | KMT2A (0.55) | L3MBTL1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015524-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF BETA-KETONITRILES | WARNER-LAMBERT COMPANY (US) | 1998-04-16 | — | — | WO | claimed |
| WO-1998015524-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF BETA-KETONITRILES | WARNER-LAMBERT COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |