Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698087 | 0.94 | L3MBTL1 (0.61) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28727176 | 0.87 | KMT2A (0.58) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13100658 | 0.86 | KMT2A (0.79) | L3MBTL1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31326036 | 0.85 | KMT2A (0.70) | L3MBTL1KMT2ANPC1RAB9ACES2 | |
| SCHEMBL31326025 | 0.85 | TSHR (0.53) | L3MBTL1KMT2ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1754734 | 0.85 | TSHR (0.53) | L3MBTL1KMT2ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8695606 | 0.84 | KMT2A (0.55) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL25525563 | 0.84 | KMT2A (0.55) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8697129 | 0.84 | KMT2A (0.53) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28727138 | 0.84 | KMT2A (0.53) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015524-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF BETA-KETONITRILES | WARNER-LAMBERT COMPANY (US) | 1998-04-16 | — | — | WO | claimed |
| CN-119504491-A | Efficient preparation method and application of optically pure beta-cyano ketone | 哈尔滨理工大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-114456086-B | Synthesis method of beta-cyano ketone | 哈尔滨理工大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-114456086-A | Synthesis method of beta-cyano ketone | 哈尔滨理工大学 | 2022-05-10 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |
| WO-1998015524-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF BETA-KETONITRILES | WARNER-LAMBERT COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| US-5416118-A | Enzyme inhibitors | SCHERING CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0583346-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992018462-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0508425-A1 | Bicyclic amides as inhibitors of acyl-coenzyme a: cholesterol acyl transferase | SCHERING CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |