Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.55 |
| ▸ | FAP | Q12884 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699178 | 0.99 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6164069 | 0.80 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9074959 | 0.79 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9074957 | 0.78 | F2 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8698184 | 0.76 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8699172 | 0.76 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6164541 | 0.75 | F2 (0.62) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6162266 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9077049 | 0.74 | F2 (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9077052 | 0.74 | F2 (0.49) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | claimed |