Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386332 | 0.83 | HSD17B10 (0.55) | TYRTRIM24TRIM33TTRERN1 | |
| SCHEMBL29472390 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TTRKDM4EPTGS2RAB9A | |
| SCHEMBL42757 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TTRKDM4EPTGS2RAB9A | |
| Hydrochloric Acid SCHEMBL30783012 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TTRKDM4EPTGS2RAB9A | |
| SCHEMBL30335110 | 0.77 | TYR (0.61) | TYRTRIM24TRIM33TTRBACE1 | |
| SCHEMBL93513 | 0.77 | TYR (0.61) | TYRTRIM24TRIM33TTRBACE1 | |
| SCHEMBL27645627 | 0.77 | TYR (0.61) | TYRTRIM24TRIM33TTRBACE1 | |
| SCHEMBL11417982 | 0.75 | TYR (0.59) | TYRTRIM24TRIM33TTRBACE1 | |
| Hydrochloric Acid SCHEMBL8726620 | 0.75 | TYR (0.59) | TYRTRIM24TRIM33TTRBACE1 | |
| SCHEMBL28816082 | 0.75 | TYR (0.59) | TYRTRIM24TRIM33TTRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |